Zyban helps people stop smoking by reducing cravings and other withdrawal effects. Learn about side effects, interactions and indications. Bupropion is used to treat major depressive disorder (MDD) and to prevent seasonal affective disorder (SAD), which is sometimes called autumn-winter seasonal depression. It is also used as part of a support program to help people stop smoking. Bupropion is sold under different brand names. Bupropion extended-release (SR), brand name Zyban, is an atypical antidepressant. It's taken by adults for smoking cessation (quitting smoking) only. It works by easing symptoms of nicotine withdrawal and lowering your cravings for nicotine. Zyban is a brand of bupropion, which is a medication that helps you quit smoking. It works by reducing cravings for nicotine. Zyban (Bupropion Hcl) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. Bupropion is the active ingredient in Wellbutrin and Zyban, Auvelity contains bupropion and dextromethorphan, and Contrave contains bupropion and naltrexone. Bupropion improves mood regulation and nicotine cravings and, when combined with naltrexone, helps reduce food intake. Zyban is a nicotine-free quit aid available by prescription-only. Learn how it can help reduce your urge to smoke, as well as usage information and side effects. DESCRIPTION ZYBAN (bupropion hydrochloride) Sustained-Release Tablets are a non-nicotine aid to smoking cessation. ZYBAN is chemically unrelated to nicotine or other agents currently used in. Find patient medical information for Bupropion (Wellbutrin, Zyban, and others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Wellbutrin SR and XL are available in generic form in the United States and Canada. In 1997, bupropion was approved by the FDA for use as a smoking cessation aid under the name Zyban. [197][195] In 2006, Wellbutrin XL was similarly approved as a treatment for seasonal affective disorder. [198][199].